id author title date pages extension mime words sentences flesch summary cache txt cord-316745-n10ia3j3 Liu, HongDe A new approach to the prediction of transmembrane structures 2008-05-23 .txt text/plain 1828 133 61 In this paper, a new approach, maximum spectrum of continuous wavelet transform (MSCWT), is proposed to predict TMHs. The predictions for eight SARS-CoV membrane proteins indicate that MSCWT has the same capacity with software TMpred. In this paper, MSCWT was proposed to predict TMHs of membrane proteins. MSCWT of a signal could be obtained from the following steps: firstly, choose an appreciated mother wavelet and an appreciated scale range to perform CWT; then, detect and record the CWT maximum at every translation; finally, plot the recorded maximum value to its position (translation). Figure 1 shows the TMHs predicted by MSCWT and TMpred for SARS-CoV protein Orf9 and Orf14. MSCWT has the highest accuracy rate of membrane protein sequence (84.6%), while TMpred and DAS are 75.4% and 80.0%, respectively. In this paper, the proposed new method MSCWT shows a good efficiency in predicting the positions and amounts of TMHs of membrane protein. ./cache/cord-316745-n10ia3j3.txt ./txt/cord-316745-n10ia3j3.txt