id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-280360-rh37d5wc	Gibson, David S.	Comparative analysis of synovial fluid and plasma proteomes in juvenile arthritis – Proteomic patterns of joint inflammation in early stage disease	2009-05-02		.txt	text/plain	8297	388	41	title: Comparative analysis of synovial fluid and plasma proteomes in juvenile arthritis – Proteomic patterns of joint inflammation in early stage disease Comparative analysis of synovial fluid and plasma proteomes in juvenile arthritis -Proteomic patterns of joint inflammation in early stage disease 1 We initially performed a study of the proteins expressed within synovial fluid and plasma in early JIA in order to discover novel biomarkers which distinguish between local and systemic components of joint inflammation in arthritis. The simultaneous analysis of individual paired plasma and synovial fluids from ten patients ( Table 1 , study group A) was used to initially isolate joint-specific protein expression profiles, without introducing bias from inter-individual differences. A number of proteins with consistent synovial and plasma 'specific' expression patterns are highlighted and quantified to demonstrate the ability to reliably differentiate molecular fingerprints of local and systemic disease across patient groups by this gel based approach.	./cache/cord-280360-rh37d5wc.txt	./txt/cord-280360-rh37d5wc.txt