id author title date pages extension mime words sentences flesch summary cache txt cord-268239-neb6xxlf Illiano, Anna Protein Glycosylation Investigated by Mass Spectrometry: An Overview 2020-08-28 .txt text/plain 9540 442 34 For example, the alanine-proline-rich antigen (Apa) glycoprotein, expressed on the cell surface of different Mycobacteria species, induced glycan-specific T-cell response, whereas the non-glycosylated form of the same protein in Escherichia coli showed reduced stimulation of the CD4 + T-cell system compared to the native antigen, giving evidence of the crucial involvement of glycosylation in T-cell activation by Apa during infection [42] . Technological breakthroughs in mass spectrometric analysis for specific glycan epitopes provide a more molecular approach to examine potential changes in glycosylation or to display a sufficient degree of alteration in glycosylation, as mixtures of commonly occurring glycosylation patterns associated with normal cells or tumor-associated signals [82, 84] . ./cache/cord-268239-neb6xxlf.txt ./txt/cord-268239-neb6xxlf.txt