id author title date pages extension mime words sentences flesch summary cache txt cord-256316-1odgm6hm Godet, Murielle TGEV corona virus ORF4 encodes a membrane protein that is incorporated into virions 1992-06-30 .txt text/plain 5433 269 48 Several lines of evidence lend support to the view that a gene encoding an SM-like protein is a common feature of the coronavirus genomes: (i) an ORF predicting a polypeptide with striking similarities to TGEV ORF4 was identified in the genome sequence of each of the 5 coronaviruses examined (Fig. 9 ) and the fact that TGEV SM was recognized by anti-FIPV antibodies argues for the presence of a related gene also in feline infectious peritonitis virus genome; (ii) the product expressed from the relevant MHV, BCV, and IBV ORFs was reported to have properties of a transmembrane polypeptide (Leibowitz et a/., 1988; Smith et al., 1990; Abraham et a/., 1990) ; and (iii) although expressed through a mono-, di-, or tricistronic mRNA (Abraham et a/., 1990; Budzilowicz and Weiss, 1987; Liu et al., 1991 ) the assumed SM-encoding genes are all located upstream and adjacent to the M protein gene. ./cache/cord-256316-1odgm6hm.txt ./txt/cord-256316-1odgm6hm.txt