id author title date pages extension mime words sentences flesch summary cache txt cord-018018-2yyv8vuy Rybicki, Ed History and Promise of Plant-Made Vaccines for Animals 2018-07-04 .txt text/plain 9127 314 37 1995) was also used to demonstrate the efficacy of two very different plant-made papillomavirus vaccines, a few years after the demonstration that Human papillomavirus L1 major capsid protein virus-like particles could be produced in transgenic tobacco or potato (Biemelt et al. The early historical account of molecular farming for veterinary vaccines given above gives an idea of the array of technologies available and used up to the mid-2000s: transgenic and transplastomic expression of subunit proteins; recombinant plant viruses either used to express whole vaccine candidate genes, or to display chosen peptides fused to their capsid proteins; fusion of vaccine protein genes to carrier proteins to improve immunogenicity, including by inherent adjuvant properties; candidate parenteral and oral vaccines to both viruses and bacteria; therapeutics for animals made in plants; use of plant cell cultures to make antigens. ./cache/cord-018018-2yyv8vuy.txt ./txt/cord-018018-2yyv8vuy.txt