id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-014901-d9szap94	Permyakova, N. V.	State of research in the field of the creation of plant vaccines for veterinary use	2015-01-04		.txt	text/plain	8091	343	41	Transgenic plants as an alternative of costly systems of recombinant immunogenic protein expression are the source for the production of cheap and highly efficient biotherapeuticals of new generation, including plant vaccines. Of principal importance of this work development was the creation of the "edible vaccine" concept, the essence of which is the use of genetically modified plants containing protein anti gens of infectious agents for oral delivery of relevant antigens to the mucosa of the gastrointestinal tract of warm blooded animals. Preparation of medicinal substances for the pro duction of veterinary products is based on various approaches, including biotechnology using genetically modified (transgenic) organisms for these purposes; such expression systems as bacteria, yeast, cells of insects and mammals are used. This review is devoted to the analysis of possibilities of producing recombinant immunogenic proteins for veterinary use on the basis of plant expression systems, and the history of the concept of "edible vaccines" for animal immunization.	./cache/cord-014901-d9szap94.txt	./txt/cord-014901-d9szap94.txt