id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-014368-4nasrbs6	nan	Gene Chip for Viral Discovery	2003-11-17		.txt	text/plain	10009	438	49	As they report in this paper, Miguel Nicolelis and colleagues have helped clarify some of the fundamental issues surrounding the programming and use of BMIs. Presenting results from a series of long-term studies in monkeys, they demonstrate that the same set of brain cells can control two distinct movements, the reaching and grasping of a robotic arm. RAG genes regulate the genetic recombination and ultimate cell surface expression of TCRs. Using chemical inhibitors and mutant human T cell lines deficient in critical signaling components involved in antigen receptor-dependent pathways, the researchers found that the loss of specific functions or specific proteins affected an unexpected set of target genes. But these studies also establish a model for investigating other signaling systems, to determine whether biologically functional basal signaling is a rare phenomenon or whether it is a fundamental cell process needed to control the profile of gene expression in the quiescent state.	./cache/cord-014368-4nasrbs6.txt	./txt/cord-014368-4nasrbs6.txt