id author title date pages extension mime words sentences flesch summary cache txt cord-253997-imwjoecx Lotter-Stark, Hester C.T. Plant made anti-HIV microbicides—A field of opportunity 2012-12-31 .txt text/plain 11983 607 47 Protein based microbicides, namely, neutralising antibodies and peptide lectins-lend themselves to production in plants (De Muynck et al., 2010; Matoba et al., 2010; O'Keefe et al., 2009; Sexton et al., 2006) . However the four well-known HIV-1 neutralising antibodies, namely, 2G12, 4E10, 2F5 and b12 have been well researched in terms of structure, interaction with the virus, protection in animal models and safety in clinical trials and were produced in various plant platforms. coli produced and native GRFT respectively, demonstrating the potential of plant expression approaches as viable alternatives for the production of the lectin for use as a candidate microbicide. We reviewed here the progress made with the production of HIV neutralising antibodies and peptide lectins in plant systems. Although several anti-HIV neutralising antibodies and peptide lectins have been produced in plants, only two have entered clinical trials . ./cache/cord-253997-imwjoecx.txt ./txt/cord-253997-imwjoecx.txt