id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-343791-0vykwml5	Hainline, Kelly M.	Progress towards the clinical translation of bio-inspired peptide and protein assemblies	2017-11-08		.txt	text/plain	7314	416	42	These include spherical assemblies such as virus-like particles, designed protein nanoparticles, and peptide amphiphiles (Figure 1) ; and elongated structures such as β-sheet nanofibers, fiber-forming peptide amphiphiles, and filamentous phage (Figure 2) . [17, 18] Owing to their lack of a viral genome, VLP-based vaccines circumvent some risks associated Supramolecular materials composed of proteins and peptides have been receiving considerable attention toward a range of diseases and conditions from vaccines to drug delivery. [19] As alternatives to these previous platforms, VLPs were developed to display an array of epitopes that mimic the surface of native viruses more effectively than subunit or peptide vaccines, thus improving their immunogenic properties. Whereas synthetic peptides are usually not sufficiently immunogenic and require adjuvants, the Burkhard group has developed a self-assembling protein nanoparticle platform that displays both B and T cell epitopes to produce a vaccine with self-adjuvanting qualities.	./cache/cord-343791-0vykwml5.txt	./txt/cord-343791-0vykwml5.txt