id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-254404-lrsqrc2u	Yañez-Guerra, Luis Alfonso	Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling	2020-06-24		.txt	text/plain	9725	443	45	Analysis of transcriptome/genome sequence data revealed loss of NPY/NPF-type signalling, but orthologs of PrRP-type neuropeptides and sNPF/PrRP-type receptors were identified in echinoderms. A more recent finding was the discovery of a family neuropeptide precursor-type proteins in echinoderms that contain a peptide that shares sequence similarity with NPY/NPF-type peptides (Zandawala et al., 2017) . rubens neuropeptide and orthologs from other echinoderms with related peptides in other taxa revealed that they share sequence similarity with both PrRP-type neuropeptides ( Figure 1A ) and with NPY/NPF-type neuropeptides ( Figure 1B) . In echinoderm PrRP-like peptide genes, the exon encoding the neuropeptide is likewise interrupted by an intron but it is located in a different position to the intron that interrupts the coding sequence for NPY/NPF-type peptides. Subsequently, analysis of transcriptomic/genomic sequence data has enabled identification of NPY/NPF-type neuropeptides and their cognate receptors in a variety of invertebrate taxa, revealing a high level of conservation of this signalling system in bilaterian phyla (Zatylny-Gaudin and Favrel, 2014; Fadda et al., 2019) .	./cache/cord-254404-lrsqrc2u.txt	./txt/cord-254404-lrsqrc2u.txt