id author title date pages extension mime words sentences flesch summary cache txt cord-292734-2g2ym81n Jung, Kwonil Impact of porcine group A rotavirus co-infection on porcine epidemic diarrhea virus pathogenicity in piglets 2008-06-30 .txt text/plain 3251 160 58 The piglets were euthanized at 1, 2, or 3 days post-inoculation (DPI) to measure the villous height:crypt depth (VH:CD) ratio and to collect fecal samples for RT-PCR and virus isolation. No significant differences in mean VH:CD ratio and clinical symptoms (diarrhea, vomiting, dehydration, and anorexia) were observed between the PEDV/PGAR-infected and PEDV-infected groups of piglets at 1, 2 and 3 DPI; however, at 2 and 3 DPI, PGAR was detected in all fecal samples by RT-PCR and virus isolation. The aim of this study was to determine the impact of PGAR co-infection on PEDV pathogenicity by subjecting piglets experimentally co-infected by PEDV and PGAR to evaluation of clinical signs (severity in diarrhea, dehydration, and dehydration) and histological morphometric analysis (villous height: crypt depth) in mid-jejunum where PEDV lesions were evident. ./cache/cord-292734-2g2ym81n.txt ./txt/cord-292734-2g2ym81n.txt