id author title date pages extension mime words sentences flesch summary cache txt cord-292690-1p1gnpgf Zang, Yue Recombinant Lactobacillus acidophilus expressing S(1) and S(2) domains of porcine epidemic diarrhea virus could improve the humoral and mucosal immune levels in mice and sows inoculated orally 2020-08-16 .txt text/plain 5004 237 50 title: Recombinant Lactobacillus acidophilus expressing S(1) and S(2) domains of porcine epidemic diarrhea virus could improve the humoral and mucosal immune levels in mice and sows inoculated orally In order to develop a new effective vaccine for the current PEDV, oral vaccines were generated by transferring eukaryotic expression recombinant plasmids carrying the S(1) and S(2) (antigenic sites of the S protein) epitopes of PEDV into a swine-origin Lactobacillus acidophilus (L. The results showed that oral administration of the VP1 gene of foot-and-mouth disease virus using Lactobacillus as a carrier could produce a higher antibody titer than injection, and induce humoral and cellular immunity (Li et al., 2007) . High-level mucosal and systemic immune responses induced by oral administration with Lactobacillus-expressed porcine J o u r n a l P r e -p r o o f epidemic diarrhea virus (PEDV) ./cache/cord-292690-1p1gnpgf.txt ./txt/cord-292690-1p1gnpgf.txt