id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-356370-jjl1hbeb	Sahajpal, Nikhil Shri	Role of clinical laboratories in response to the COVID-19 pandemic	2020-06-19		.txt	text/plain	1602	77	41	In response to the outbreak, several state authorities and commercial companies have developed diagnostic assays to test individuals for the SARS-CoV-2 infection. In the US, clinical laboratories are required to perform 'bridging studies' on FDA approved SARS-CoV-2 diagnostic assays to implement testing under the EUA regulation. Although, the reverse transcription-polymerase chain reaction (RT-PCR) based assays for the detection of SARS-CoV-2 nucleic acid regions might be the most practical approach at present, qualitative assays are far from providing insights into the evolution of the virus and the varied immune response in different populations. In addition, the RT-PCR based assays provide a unique opportunity to implement pooling sample strategy for wide-scale population screening for SARS-CoV-2. Several studies, including from our laboratory (under review) have demonstrated that pooling sample strategy is a practical and feasible method for screening populations for SARS-CoV-2 [2] . Laboratories should therefore prime for serologic testing by validating assays using RT-PCR confirmed COVID-19 samples.	./cache/cord-356370-jjl1hbeb.txt	./txt/cord-356370-jjl1hbeb.txt