id author title date pages extension mime words sentences flesch summary cache txt cord-355489-tkvfneje Mendez, Jairo A Phylogenetic history demonstrates two different lineages of dengue type 1 virus in Colombia 2010-09-14 .txt text/plain 4615 235 48 Yet, the phylogenetic relationships between strains isolated along the covered period of time suggests that viral strains detected in some years, although belonging to the same genotype V, have different recent origins corresponding to multiple re-introduction events of viral strains that were circulating in neighbor countries. Due to the importance of DENV in public health, the particular goals of this research were to reconstruct the phylogenetic history of DENV-1 and to date the phylogenetic tree using isolation time as calibration points to establish date of introduction of virus and rate evolution patterns of virus in Colombia. Previously reported genotypes were represented in the tree and placed most of the Colombian isolates nesting in the genotype V clade (America, Africa) and were closely related to Argentina, Brazil and Paraguay virus strains. ./cache/cord-355489-tkvfneje.txt ./txt/cord-355489-tkvfneje.txt