id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-350593-bvmg7f15	McDonald, R.S.	Proportional mouse model for aerosol infection by influenza	2012-08-21		.txt	text/plain	6550	324	49	CONCLUSIONS: MID (50) for inspired H1N1 aerosols in CD‐1 mice is between 12 and 40 TCID (50); proportionality to dose of weight loss and viral populations makes the CD‐1 mouse a useful model for measuring infectivity by inhalation. Although a few publications have documented the transmissibility of influenza A through inhalation routes (Tellier 2006 (Tellier , 2009 , few studies to date have utilized a mouse model to investigate susceptibility to and pathogenicity of measured aerosol exposures. Table 2 Results of three assays [PCR, direct fluorescent antibody assay (DFA) and CPE] from the homogenates of CD-1 murine lung tissue exposed to an aerosol generated from 1Á58 9 10 6 TCID 50 ml À1 At the 3-min exposure time, no mice were positive for influenza virus as determined by Ct value.	./cache/cord-350593-bvmg7f15.txt	./txt/cord-350593-bvmg7f15.txt