id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-345211-4ivqlsgt	Murdoch, David R.	How recent advances in molecular tests could impact the diagnosis of pneumonia	2016-03-07		.txt	text/plain	5994	295	35	Guidelines for the management of community-acquired pneumonia in children are even more restrictive, again recommending that tests should mainly be used on patients with severe disease, with a focus on blood cultures and detection of respiratory viruses [11, 12] . While not exactly new (polymerase chain reaction (PCR) assays for respiratory pathogens have been around for over 20 years), the widespread adoption of nucleic acid detection tests (NATs) by diagnostic laboratories has been relatively slow. The NATs that are most widely used in diagnostic laboratories are those that detect potential pneumonia pathogens that are not part of the normal flora, namely respiratory viruses and selected non-colonizing bacteria. Quantitative multiplex PCR has been used to determine the etiology of community-acquired pneumonia in adults using cutoffs developed for interpretation of culture results from lower respiratory tract specimens [85, 86] .	./cache/cord-345211-4ivqlsgt.txt	./txt/cord-345211-4ivqlsgt.txt