id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344751-i4qnrtjq	Van Praet, Jens T.	Comparison of four commercial SARS-CoV-2 IgG immuno-assays in RT-PCR negative patients with suspect CT findings	2020-09-10		.txt	text/plain	2399	119	49	Clinical specificity for Covid-19 of some N protein-based immuno-assays was suboptimal, as positive results were observed in control patients with recent common human coronavirus, influenza B and adenovirus infections. To evaluate the specificity of the immuno-assays, we used a set of serum samples from control patients with recent respiratory viral or atypical bacterial infections. To this end, we tested for cross-reactivity with sera of patients with other respiratory viral or atypical bacterial infections, including common coronavirus infections, since these may present with clinical and radiological findings similar to Covid-19. Our study focused on the clinical sensitivity and specificity of four commercial immuno-assays for anti-SARS-COV-2 IgG in the subset of patients presenting with negative RT-PCR and suspect CT findings. In summary, we found good clinical sensitivity of anti-SARS-Cov-2 IgG immunoassays for Covid-19 in the subset of patients with negative RT-PCR 14 days after onset of symptoms.	./cache/cord-344751-i4qnrtjq.txt	./txt/cord-344751-i4qnrtjq.txt