id author title date pages extension mime words sentences flesch summary cache txt cord-333805-xmqs2ax7 Romoli, Michele A systematic review of neurological manifestations of SARS‐CoV‐2 infection: the devil is hidden in the details 2020-06-05 .txt text/plain 4025 257 44 BACKGROUND: We systematically reviewed available evidence for reports of neurological signs and symptoms in Coronavirus disease (COVID)‐19 patients to identify cases with severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection or immune‐mediated reaction in the nervous system. This study therefore aimed to identify clinical cases of confirmed nervous system invasion or postinfectious neurological disease in the available COVID-19 literature on the basis of a systematic review. A systematic review was carried out to study all cases reporting nervous system involvement in patients with proven SARS-CoV2 infection. There were just 2 cases with positive SARS-CoV-2 PCR in CSF among 27 patients with potential neurologic symptoms and proven COVID-19. In this regard, we see a clear need for the use of precise case definitions and focused diagnostic work-up to distinguish nonspecific complications of severe disease and focused reporting of neurological involvement in association with SARS-CoV-2 infection. ./cache/cord-333805-xmqs2ax7.txt ./txt/cord-333805-xmqs2ax7.txt