id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-331496-5xak7z6b	Garnett, Emily	Clinical Validation and Performance Evaluation of the Automated Vitros Total Anti–SARS-CoV-2 Antibodies Assay for Screening of Serostatus in COVID-19	2020-08-31		.txt	text/plain	3450	187	43	We anticipate it will be a useful tool in screening for exposure to SARS-CoV-2; however, the use of the CoV2T and other serologic assays in the clinical management of patients with COVID-19 is unknown and must be evaluated in future studies. In this study, we describe validation of one of the first assays to receive EUA on an automated platform, the Vitros Anti-SARS-CoV-2 Total (CoV2T; Ortho Clinical Diagnostics) antibody assay, for screening of previous exposure to SARS-CoV-2 in our patient population. Seroconversion in our patient population was assessed by correlation of chart review of 55 patients known to be positive for SARS-CoV-2 by RT-PCR and known date of symptom onset with sample reactivity by the CoV2T assay. Specimens from 14 patients with acute infections, previously tested to be negative for SARS-CoV-2 by RT-PCR but positive for another respiratory viral infection by molecular analysis, were nonreactive by the CoV2T assay.	./cache/cord-331496-5xak7z6b.txt	./txt/cord-331496-5xak7z6b.txt