id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327105-7dsgs2sd	Zóka, András	Distinct changes in the real-time PCR detectability of certain SARS-CoV-2 target sequences	2020-05-05		.txt	text/plain	341	24	58	title: Distinct changes in the real-time PCR detectability of certain SARS-CoV-2 target sequences [1] highlighted notable aspects of the PCR-based diagnosis of SARS-CoV-2 infection, namely that the PCR-based detectability of certain loci might differ significantly and change over time. In our practice we also observed that the SARS-CoV-2 PCR positivity in the oropharyngeal swabs of patients might persist for weeks [2] , however, the characteristics of positivity (including the target sequences detected) may change in a predictable manner. Our results might indicate that the detectability of the viral Orf1a-related RdRp sequence might fade more rapidly during convalescence, only later followed by the N gene. This phenomenon might affect the interpretation of the results, as detecting a lone N gene might suggest a later presentation within the course of the disease. Dynamic change process of target genes by RT-PCR testing of SARS-Cov-2 during the course of a Coronavirus Disease 2019 patient Profile of RT-PCR for SARS-CoV-2: a preliminary study from 56 COVID-19 patients	./cache/cord-327105-7dsgs2sd.txt	./txt/cord-327105-7dsgs2sd.txt