id author title date pages extension mime words sentences flesch summary cache txt cord-325068-j1lfq60o Pene, Frédéric Coronavirus 229E-Related Pneumonia in Immunocompromised Patients 2003-10-01 .txt text/plain 2583 134 35 The results of inoculation tests performed with HUH7 cells were also positive, revealing corona-like particles that were subsequently identified as coronavirus 229E by RT-PCR performed on both culture supernatant and BAL fluid specimens. However, respiratory symptoms only appeared after completion of antiviral treatment and improvement of skin eruptions, and both viral culture and PCR for VZV performed on BAL fluid specimens were negative. The prevalence of coronavirus pulmonary infections among immunocompromised patients is unknown, and it is probably largely underestimated in the absence of the routine performance of sensitive cell culture, RT-PCR, or electron microscopy on BAL fluid specimens. Thus, only 1 case of coronavirus-associated pneumonia was previously described in an immunocompromised patient following autologous bone marrow transplantation, with the diagnosis based on the presence of viral particles in BAL fluid specimens [22] . ./cache/cord-325068-j1lfq60o.txt ./txt/cord-325068-j1lfq60o.txt