id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-322657-q4aeood2	Jartti, Tuomas	Respiratory Picornaviruses and Respiratory Syncytial Virus as Causative Agents of Acute Expiratory Wheezing in Children	2004-06-17		.txt	text/plain	3169	177	45	We studied the viral etiology of acute expiratory wheezing (bronchiolitis, acute asthma) in 293 hospitalized children in a 2-year prospective study in Finland. To prevent and treat acute expiratory wheezing illnesses in children, efforts should be focused on RSV, enterovirus, and rhinovirus infections. The purpose of the study was to investigate the role of 11 respiratory viruses in children hospitalized for acute expiratory wheezing. The supernatants of cell cultures exhibiting a cytopathogenic effect were further studied by antigen detection for adenovirus; influenza A and B viruses; parainfluenza virus types 1, 2, and 3; and RSV or by reverse transcription (RT)-PCR for enterovirus-es and rhinovirus. First, respiratory virus infection was detected in up to 90% of hospitalized children with acute expiratory wheezing. In conclusion, this study showed that acute expiratory wheezing necessitating hospitalization was most often associated with RSV, enterovirus, and rhinovirus infections.	./cache/cord-322657-q4aeood2.txt	./txt/cord-322657-q4aeood2.txt