id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-321432-qi2knswx	Gardner, Shea N	A microbial detection array (MDA) for viral and bacterial detection	2010-11-25		.txt	text/plain	8427	397	50	METHODS: We designed a pan-Microbial Detection Array (MDA) to detect all known viruses (including phages), bacteria and plasmids and developed a novel statistical analysis method to identify mixtures of organisms from complex samples hybridized to the array. We also present a novel statistical algorithm for analysis of detection/discovery arrays, which combines a predictive model of probe hybridization with a greedy likelihood maximization procedure to identify the combination of targets in a complex sample that best explains the observed probe intensity pattern. We developed a novel statistical method for detection array analysis, by modeling the likelihood of the observed probe intensities as a function of the combination of targets present in the sample, and performing greedy maximization to find a locally optimal set of targets; the details of the algorithm are shown in Methods.	./cache/cord-321432-qi2knswx.txt	./txt/cord-321432-qi2knswx.txt