id author title date pages extension mime words sentences flesch summary cache txt cord-311801-m2otfdjw Wang, Pei Combination of Serological Total Antibody and RT-PCR Test for Detection of SARS-CoV-2 Infections 2020-06-15 .txt text/plain 2724 184 62 The purpose of this study was to investigate the feasibility of serological total antibody tests combined with RT-PCR for detection of SARS-CoV-2. Serum samples and throat swabs were collected from 375 patients for total antibody testing against SARS-CoV-2 and RT-PCR analysis, respectively. This study supported the advantage of the combined method for detection of SARS-CoV-2 with a high degree of sensitivity and specificity, as a useful tool for accurate diagnosis and timely treatment of suspected patients, epidemiological investigation, as well as monitoring ongoing outbreaks of infections with SARS-CoV-2. In this study, we presented the results of two diagnostic methods: serum total antibody assays against SARS-CoV-2 by CMIA and the RT-PCR for detection of viral RNA. In addition, the combination of the results of the total antibody test and RT-PCR was discussed for detection of SARS-CoV-2 infections. Sensitivity, specificity for detection of SARS-CoV-2 by RT-PCR, and the total antibody test method as well as the combined methods were analysed. ./cache/cord-311801-m2otfdjw.txt ./txt/cord-311801-m2otfdjw.txt