id author title date pages extension mime words sentences flesch summary cache txt cord-306605-mnafslqw Gibson, CS Fetal exposure to herpesviruses may be associated with pregnancy‐induced hypertensive disorders and preterm birth in a Caucasian population 2008-02-06 .txt text/plain 4772 281 49 Objective To investigate the role of fetal viral infection in the development of a range of adverse pregnancy outcomes (APOs), including pregnancy‐induced hypertensive disorders (PIHD), antepartum haemorrhage (APH), birthweight <10th percentile (small for gestational age, SGA) and preterm birth (PTB). Main outcome measure Odds ratios and 95% CIs for specific APOs. Results For both term and PTBs, the risk of developing PIHD was increased in the presence of DNA from Herpes PCR group B viruses (OR 3.57, 95% CI 1.10–11.70), CMV (OR 3.89, 95% CI 1.67–9.06), any herpesvirus (OR 5.70, 95% CI 1.85–17.57) and any virus (OR 5.17, 95% CI 1.68–15.94). 2, 3 It has been postulated that fetal viral infection in utero may increase the risk of adverse pregnancy outcomes (APOs), such as pregnancy-induced hypertensive disorders (PIHD), birthweight <10th percentile (small for gestational age, SGA) and preterm birth (PTB). This study investigated the role of fetal exposure to viral infection (detected through the presence of viral nucleic acids in newborn screening cards) in APOs, including SGA, PIHD, antepartum haemorrhage (APH) and PTB. ./cache/cord-306605-mnafslqw.txt ./txt/cord-306605-mnafslqw.txt