id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-305462-2wz1f6k6	Beckham, J. David	Respiratory viral infections in patients with chronic, obstructive pulmonary disease	2004-09-22		.txt	text/plain	3215	191	43	OBJECTIVES: The purpose of the present study was to apply reverse transcription-PCR (RT-PCR) assays to clinical specimens collected from patients with acute respiratory illness and chronic obstructive pulmonary disease (COPD). METHODS: One hundred and ninety-four samples from two different study cohorts were analysed using RT-PCR assays for picornaviruses, coronaviruses 229E and OC43, influenza A and B viruses, respiratory syncytial virus, parainfluenza types 1–3 viruses, and human metapneumovirus and a PCR assay for adenoviruses. 11 The number of respiratory viral infections identified in asthmatic patients with acute exacerbations of disease increase significantly when RT-PCR assays are used in addition to other diagnostic methods. 3 In order to extend our understanding of the prevalence of respiratory viral infection in acute respiratory illnesses in patients with COPD, we used RT-PCR assays to evaluate samples from the previous two prospective studies for evidence of respiratory virus infection.	./cache/cord-305462-2wz1f6k6.txt	./txt/cord-305462-2wz1f6k6.txt