id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-294546-0otd1heg	Prendki, V.	Accuracy of comprehensive PCR analysis of nasopharyngeal and oropharyngeal swabs for CT-scan-confirmed pneumonia in elderly patients: a prospective cohort study	2019-01-12		.txt	text/plain	3021	169	39	CONCLUSION: Comprehensive molecular testing of NPS increases the number of pathogens detected compared with routine methods, but results are poorly predictive of the presence of pneumonia. showed in a randomized controlled trial (107 individuals with lower respiratory tract infections, mean age 65 years) that PCR for viruses and atypical bacteria in nasopharyngeal and oropharyngeal swabs (NPS) allowed the identification of additional pathogens but did not reduce antibiotic use or costs [7] . Individuals admitted to hospital for suspected pneumonia had NPS collected at inclusion for the detection of multiple bacterial and viral pathogens using multiplex PCR (comprehensive molecular testing), in addition to routine testing. Demographic data, co-morbidities, vital signs, clinical findings, severity scores, results of standard laboratory tests, blood, sputum and urine cultures, urinary antigen detection, PCR for respiratory viruses on NPS, and antimicrobial therapy administered were recorded prospectively.	./cache/cord-294546-0otd1heg.txt	./txt/cord-294546-0otd1heg.txt