id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-292347-d7xq7x5g	Carter, Linda J.	Assay Techniques and Test Development for COVID-19 Diagnosis	2020-04-30		.txt	text/plain	3426	227	51	375 While RT-PCR-based viral RNA detection has been widely 376 used in diagnosis of COVID-19, it cannot be used to monitor 377 the progress of the disease stages and cannot be applied to 378 broad identification of past infection and immunity. 46,47 410 The determination of SARS-CoV-2 exposure relies largely 411 on the detection of either IgM or IgG antibodies that are 412 specific for various viral antigens including, but not exclusively, 413 the spike glycoprotein (S1 and S2 subunits, receptor-binding 414 domain) and nucleocapsid protein. While RT-PCR has been 571 the dominant technique for detection of viral RNA, other 572 nucleic acid assays including isothermal amplification assays, 573 hybridization microarray assays, amplicon-based metagenomics 574 sequencing, and the cutting-edge CRISPR-related technologies 575 are also under development or have resulted in approved 576 tests.	./cache/cord-292347-d7xq7x5g.txt	./txt/cord-292347-d7xq7x5g.txt