id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-289745-qtorq2qq	Esper, Frank	Evidence of a Novel Human Coronavirus That Is Associated with Respiratory Tract Disease in Infants and Young Children	2005-02-15		.txt	text/plain	3627	205	53	We sought to determine whether novel human coronaviruses (HCoVs) are circulating in New Haven, Connecticut, and, if so, whether they are associated with respiratory tract disease in infants and young children. To determine whether novel HCoVs are circulating and, if so, whether they are responsible for respiratory tract disease in children, we developed a strategy to screen for previously unknown HCoVs. Our initial assumption was that all CoVs must have conserved functions and that these conserved functions are reflected in the genome. These specimens, which were obtained from both ambulatory and hospitalized patients, were screened for presence of human metapneumovirus (hMPV) by use of an RT-PCR-based approach described elsewhere [12, 13] and were submitted to the Clinical Virology Laboratory, Yale-New Haven Hospital, for diagnostic testing. The novel HCoV identified in New Haven and The Netherlands was associated with both upper and lower respiratory tract disease in infants and young children.	./cache/cord-289745-qtorq2qq.txt	./txt/cord-289745-qtorq2qq.txt