id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-277659-afysef1e	Hamilton, F.	Kinetics and performance of the Abbott Architect SARS-CoV-2 IgG antibody assay	2020-07-04		.txt	text/plain	3096	203	53	Objectives: To assess the performance (sensitivity and specificity) of the Abbott Architect SARS-CoV-2 IgG antibody assay across three clinical settings. Methods: Antibody testing was performed on three clinical cohorts of COVID-19 disease: hospitalised patients with PCR confirmation, hospitalized patients with a clinical diagnosis but negative PCR, and symptomatic healthcare workers (HCWs). To assess the performance (sensitivity and specificity) of the Abbott Architect SARS-CoV-2 IgG antibody assay across three clinical settings. Antibody testing was performed on three clinical cohorts of COVID-19 disease: hospitalised patients with PCR confirmation, hospitalized patients with a clinical diagnosis but negative PCR, and symptomatic healthcare workers (HCW's). In this paper, we report the kinetics and performance of this assay in three populations: confirmed (PCR +ve) and suspected COVID-19 patients, confirmed (PCR +ve) healthcare workers, and pre-pandemic controls with respiratory infection. The sensitivity of the Abbott SARS-CoV-2 IgG assay was estimated with 95% Confidence Intervals at different time points post symptom onset (DISCOVER patients) or first PCR positive result (healthcare workers).	./cache/cord-277659-afysef1e.txt	./txt/cord-277659-afysef1e.txt