id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-266156-xmf4emln	Miller, Tyler E.	Clinical sensitivity and interpretation of PCR and serological COVID‐19 diagnostics for patients presenting to the hospital	2020-08-28		.txt	text/plain	4329	221	45	Our goal was to examine the clinical sensitivity of two most common SARS‐CoV‐2 diagnostic test modalities, polymerase chain reaction (PCR) and serology, over the disease course to provide insight into their clinical interpretation in patients presenting to the hospital. The goal of this study is to examine the clinical sensitivity and provide insights into the interpretation of the two most common SARS-CoV-2 diagnostic test modalities: polymerase chain reaction (PCR) and serology. Serologic analysis of IgM, IgA and IgG status was performed in a subset of the above SARS-CoV-2 PCR-positive patients for which we had excess material in the MGH core laboratories for clinical validation studies. To assess the sensitivity of our serology assay over time, we tested for IgM, IgG, and IgA antibodies against the RBD of SARS-CoV-2 spike protein in 157 SARS-CoV-2 PCR-positive patients using an in-house ELISA (Table 1) .	./cache/cord-266156-xmf4emln.txt	./txt/cord-266156-xmf4emln.txt