id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261867-6n0g3bz5	Evermann, James F.	Canine Reproductive, Respiratory, and Ocular Diseases due to Canine Herpesvirus	2011-10-28		.txt	text/plain	8808	468	41	Infection rates, based on serologic studies, are high enough to explain entry of CHV into multidog environments, either as an active infection or as the result of reactivation of latent virus in environments associated with natural, or pharmacologically induced immunosuppression. In fetal and neonatal dogs with primary CHV infection, severe intraocular lesions are frequently present concurrent with systemic viral disease. The results of this study showed that topical ocular prednisolone at the concentration and treatment regimen used did not result in detectable reactivation of CHV latency, based on a combination of recrudescent clinical signs, confocal microscopy findings, ocular infectious virus shedding, real-time PCR findings, and serologic response. Primary and recurrent CHV infection in mature dogs is associated with mucosal viral shedding that it detectable by PCR assay or virus isolation. Experimental recurrent ocular CHV infection induced by systemic corticosteroid administration to dogs recovered from primary ocular infection again resulted in viral shedding.	./cache/cord-261867-6n0g3bz5.txt	./txt/cord-261867-6n0g3bz5.txt