id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-258768-bjjfkfgg	McElligott, Susan	Detection and genetic characterization of canine parvoviruses and coronaviruses in southern Ireland	2010-11-24		.txt	text/plain	4380	220	53	Two hundred fifty samples were collected in total, Fig. 2 Phylogenetic tree based on partial S gene nucleotide sequences of CCoVs described in this study and reference strains. As a result of RNA recombination, insertions, deletions and a high susceptibility to frequent mutation, coronaviruses can mutate rapidly, leading to new genotypes (CCoV-I), biotypes (pantropic CCoV) and host variants (canine respiratory coronavirus), all of which may present possible difficulties regarding successful vaccination of dogs. As a result of this study, it can be concluded that although it appears that the viral evolution of CPV type 2 is not yet a significant problem for the canine population in Ireland, vaccine efficacy may need to be re-evaluated by the animal healthcare industry, as it is a possibility that the new CPV-2c strain will eventually emerge into the population as a result of importing dogs from other parts of the world.	./cache/cord-258768-bjjfkfgg.txt	./txt/cord-258768-bjjfkfgg.txt