id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-015941-4fz79wzf	Hu, Yuan	Molecular Techniques for Blood and Blood Product Screening	2018-11-10		.txt	text/plain	7210	381	50	Through the application of molecular biology, biological and biochemical analyses have been revolutionized, and nucleic acid, gene-based techniques have been developed to screen blood and plasma donations for evidence of very recent and earlier viral infections that might otherwise be missed by conventional serologic testing. Because NAT detects a virus's genetic material instead of waiting for the body's response, the formation of antibodies, as with many current tests, it offers the opportunity to reduce the window period during which an infecting agent is undetectable by traditional tests [21] , thus further improving blood safety. One reason for this is that currently available blood screening technologies detect core antibodies or surface antigens, which appear up to 8 weeks after infection. The anti-HBc test developed in 1987 detects an antibody to the hepatitis B virus that is produced during and after infection. Detection of HIV-1 and HCV infections among antibody-negative blood donors by nucleic acid-amplification testing	./cache/cord-015941-4fz79wzf.txt	./txt/cord-015941-4fz79wzf.txt