id author title date pages extension mime words sentences flesch summary cache txt cord-007066-zn10rnrm Park, Noh Jin Characterization of RNA in Saliva 2006-06-01 .txt text/plain 4637 285 62 RNA can enter the oral cavity through various routes, including saliva secretions from the 3 major salivary glands (the parotid, submandibular, and sublingual glands) and minor glands, gingival crevice fluid (GCF), and desquamated oral epithelial cells. It is therefore possible that the RPS9 PCR products in panels B and C of Fig. 1 are produced from both RPS9 and RPS9P2 mRNAs. Previous expression-based microarray analysis showed that 185 different transcripts were consistently detected in the supernatants of 10 healthy human saliva samples (6 ) . Although individual variations exist, we detected ␤-actin mRNA in all 3 major salivary glands, GCF, and desquamated oral epithelial cells ( Fig. 2A) , suggesting that RNA enters the oral cavity from different sites. In addition to the saliva samples, we also measured RNA-macromolecule associations in serum and found that ϳ8% and Ͻ1% of ␤-actin mRNA could be detected in serum filtered through 0.45 and 0.22 m pores, respectively (see Fig. 1c in the online Data Supplement). ./cache/cord-007066-zn10rnrm.txt ./txt/cord-007066-zn10rnrm.txt