id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-352177-05sku8a8	Pahus, Laurie	Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?	2020-08-13		.txt	text/plain	4115	208	36	To additionally explain patient willingness to participate in new-drug studies or research associated with pharmaceutical companies or with public institutions, further models used the same predictive variables as for the first model, plus distrustgroup-membership as an additional explanatory variable. Our study aimed at evaluating variables associated with patient willingness to participate in different categories of clinical trials and at identifying a potential recruitment bias in clinical trials related to patient distrust in the pharmaceutical industry and healthcare systems. Several studies have previously evaluated such rates and highlighted that altruism, hope for personal benefit, contribution to advances in science as well as financial benefit are the main reasons for agreeing to participate, whereas fear of adverse events, impossibility to cope with the logistic constraints accompanying participation, poor knowledge about or negative perception of clinical trials and distrust in pharmaceutical industry are potential barriers [20] [21] [22] [23] . Distrust in pharmaceutical companies is associated with a specific patient profile and with refusal to participate in pre-marketing industry-sponsored drug trials.	./cache/cord-352177-05sku8a8.txt	./txt/cord-352177-05sku8a8.txt