id author title date pages extension mime words sentences flesch summary cache txt cord-347414-t88654wo Peng, Mian Successful management of seven cases of critical COVID-19 with early noninvasive-invasive sequential ventilation algorithm and bundle pharmacotherapy 2020-08-06 .txt text/plain 2750 134 46 title: Successful management of seven cases of critical COVID-19 with early noninvasive-invasive sequential ventilation algorithm and bundle pharmacotherapy We report the clinical and laboratory findings and successful management of seven patients with critical coronavirus disease 2019 (COVID-19) requiring mechanical ventilation (MV). Upon diagnosis with COVID-19 of critical severity, the patients were admitted to the intensive care unit, where they received early noninvasive–invasive sequential ventilation, early prone positioning, and bundle pharmacotherapy regimen, which consists of antiviral, anti-inflammation, immune-enhancing, and complication-prophylaxis medicines. Here, we report the successful management of seven critically ill patients diagnosed with COVID-19 who suffered acute respiratory failure. Good treatment outcomes can be achieved for critically ill patients with COVID-19 with early sequential noninvasive-invasive ventilation and bundle pharmacotherapy, which comprises antiviral and anti-inflammation medicines, immune system support, and prophylaxis for vascular complications. ./cache/cord-347414-t88654wo.txt ./txt/cord-347414-t88654wo.txt