id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-346558-u1e0kzmm	Cattaruzza, Maria Sofia	Tobacco smoking and COVID-19 pandemic: old and new issues. A summary of the evidence from the scientific literature	2020-05-11		.txt	text/plain	3534	164	48	Since in China smoking habit differs according to gender (52.1% of men and only 2.7% of women regularly smoke (22)), Chinese men have higher prevalence of comorbidities and a higher rate of severe or fatal outcomes in COVID-19 pandemic, tobacco smoking has been hypothesized to be an important risk factor for poor prognosis (3, 4) . A systematic review and meta-analysis (published in pre-print in April, 2020), focusing on smoking and COVID-19 progression, evaluated 12 studies (but not their quality on smoking data) and reported severe disease progression in 17.8% of smokers in comparison to 9.3% of non-smokers and a statistically significant association between smoking and disease severity (OR = 2.25, 95% confidence interval, CI: 1.49-3.39); nevertheless, out of 9025 patients only 495 (5.5%) were ever smokers (27) . A very recent systematic review (also published in pre-print in April 2020), tried to clarify the role of smoking on infection, hospitalization, disease severity and mortality from COVID-19 and summarized the main findings emerged so far (31) .	./cache/cord-346558-u1e0kzmm.txt	./txt/cord-346558-u1e0kzmm.txt