id author title date pages extension mime words sentences flesch summary cache txt cord-327989-6p39cx2e Everaert, Bert Emerging cardiological issues during the COVID‐19 pandemic 2020-05-16 .txt text/plain 1985 110 45 2 hospitalized COVID-19 patients in Wuhan, China, presenting with elevated high-sensitive cardiac troponin I levels had a higher frequency of complications such as ARDS (58.5% vs. All rights reserved risk factors or pre-existing coronary artery disease are at high risk during this COVID-19 pandemic and that cardiac injury is an important predictor of adverse outcomes. As with other viral conditions such as influenza and SARS-CoV 4 , direct myocardial infection of the virus can lead to an acute form of viral myocarditis (1 in 3 patients presenting with SARS during the Toronto outbreak). the aforementioned New York study, true obstructive myocardial infarctions do occur, as many patients with COVID-19 present with underlying cardiovascular disease or cardiac risk factors. 11 Moreover, in animal studies of SARS-CoV-1 and ARDS, ACE2 as well as ARB treatment (losartan) improved the acute lung injury 12, 13 and clinical studies in COVID-19 patients with these agents are currently active and recruiting patients (NCT04287686 and NCT04312009 or NCT04311177, respectively). ./cache/cord-327989-6p39cx2e.txt ./txt/cord-327989-6p39cx2e.txt