id author title date pages extension mime words sentences flesch summary cache txt cord-320788-ln8ddyuj Wang, Chun-Hua Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS 2005-05-11 .txt text/plain 4399 229 49 BACKGROUND: During the acute phase of severe acute respiratory syndrome (SARS), mononuclear cells infiltration, alveolar cell desquamation and hyaline membrane formation have been described, together with dysregulation of plasma cytokine levels. In the current study, we conducted a study to examine HRCT changes in patients who recovered from the acute phase of SARS at days 60 and 90, and measured the associated inflammatory profiles directly by examining bronchoalveolar lavage fluid (BALF). At 60 days, compared to normal subjects, there was a significant increase in total cell counts in BAL fluid from SARS patients (Table 3 ) with a significant increase in alveolar macrophages (AM) and lymphocytes., The proportion of CD8+ T cells was increased to a greater extent than CD4+ T cells, leading to a significant decrease in CD4/CD8 ratio (Table 4 ). Coronavirus infected cells were not detected in any of SARS patients with low HRCT score or in normal subjects (Table 1) . ./cache/cord-320788-ln8ddyuj.txt ./txt/cord-320788-ln8ddyuj.txt