id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-319615-p2labgd8	Schulman, Sam	Coronavirus Disease 2019, Prothrombotic Factors, and Venous Thromboembolism	2020-05-11		.txt	text/plain	3048	186	49	Several studies have shown that the severely ill patients have high or very high Ddimer values, and a hypercoagulable state has been described with, in some cases, development of disseminated intravascular coagulation (DIC). 2, 3 Subsequently, European physicians have reported a higher incidence of thromboembolic events, mainly venous, in patients with COVID-19 pneumonia in the intensive care unit (ICU). • Does the hypercoagulability result in a higher incidence of thromboembolism than in other patients with severe infection in the ICU? 6 A meta-analysis of 30 studies and 53,000 patients reported that increased D-dimer was associated with severe COVID-19 infection, with a p-value of < 0.001. At three hospitals in the Netherlands, all patients with COVID-19 pneumonia admitted to the ICU were evaluated for venous and arterial thromboembolic complications. In most of the studies from China, it is not reported whether, and in such cases how many, patients received chemoprophylaxis against venous thromboembolism and at what dose.	./cache/cord-319615-p2labgd8.txt	./txt/cord-319615-p2labgd8.txt