id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-310690-50z2kdaj	Maschmeyer, Georg	How to manage lung infiltrates in adults suffering from haematological malignancies outside allogeneic haematopoietic stem cell transplantation	2016-01-05		.txt	text/plain	6462	302	35	• The early detection of lesions indicating invasive mould disease or Pneumocystis pneumonia (PcP) facilitates targeted bronchoalveolar lavage (BAL) and prompt institution of pre-emptive antimicrobial treatment, resulting in improved survival of these patients (Guo et al, 2014) ; • CT findings, such as consolidation, small nodules with or without a typical or reversed 'halo sign' and 'air-crescent sign', may be important signs of filamentous fungal disease. Nodular or cavitary lesions indicate an invasive 'mould' disease, while differential diagnoses include pneumonia caused by other microorganisms, such as mycobacteria (in patients from high prevalence areas), Nocardia, Pneumocystis jirovecii or Pseudomonas aeruginosa and infiltrates by the underlying malignancy (Shorr et al, 2004) . Clinical outcome of proven invasive mould infection (aspergillosis or mucormycosis) in neutropenic patients is poor (Lin et al, 2001) , so that early mould-active antifungal treatment should be added to a broad-spectrum anti-pseudomonal beta-lactam in patients whose LI do not have the typical radiological pattern of PcP or lobar bacterial pneumonia (Maschmeyer et al, 2015) .	./cache/cord-310690-50z2kdaj.txt	./txt/cord-310690-50z2kdaj.txt