id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-303349-0kn7apl3	Lippi, Giuseppe	Hemoglobin value may be decreased in patients with severe coronavirus disease 2019	2020-04-02		.txt	text/plain	874	51	55	1 The clinical characteristics of this pandemic disease may be complicated by the onset of a severe form of intestinal pneumonia in 10-15% of infected patients, which may then progress toward acute respiratory distress syndrome (ARDS) and eventually in multi-organ failure (MOF) and death. The title, abstract and full text of documents identified according to these search criteria were analyzed and those reporting information on the hemoglobin values in COVID-19 patients with or without severe disease (i.e., those needing mechanical ventilation, intensive care unit (ICU) admission or those who died), were meta-analyzed. The final meta-analysis entailed the estimation of the weighted mean difference (WMD) and 95% confidence interval (95% CI) of hemoglobin values between subjects with or without severe disease. Despite the heterogeneity observed among the available studies, the results of this meta-analysis show that hemoglobin values are essentially reduced in COVID-19 patients with severe disease, compared to those with milder forms, thus confirming previous evidence garnered from patients with other types of pneumonia.	./cache/cord-303349-0kn7apl3.txt	./txt/cord-303349-0kn7apl3.txt