id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-302215-sqrbj5r4	Vanden Eynde, Jean Jacques	COVID-19: An Update about the Discovery Clinical Trial	2020-05-14		.txt	text/plain	3336	205	49	Whereas plasma therapy attracts much interest, the European project Discovery focuses on the potentialities of small molecules like remdesivir, the combination of lopinavir/ritonavir, hydroxychloroquine, and chloroquine. . Although a decision to administer remdesivir for compassionate use was based on the case patient's worsening clinical status, randomized controlled trials are needed to determine the safety and efficacy of remdesivir and any other investigational agents for treatment of patients with 2019-nCoV infection." The authors interpreted their results in the following terms: "In this study of adult patients admitted to hospital for severe COVID-19, remdesivir was not associated with statistically significant clinical benefits. As earlier mentioned, controversial results have been published on the efficacy of treatments associating hydroxychloroquine and azithromycin for French patients hospitalized for moderate [31] or severe [32, 33] COVID-19 infection. Lopinavir-ritonavir alone or combined with arbidol in the treatment of 73 hospitalized patients with COVID-19: A pilot retrospective study	./cache/cord-302215-sqrbj5r4.txt	./txt/cord-302215-sqrbj5r4.txt