id author title date pages extension mime words sentences flesch summary cache txt cord-284979-lyt98od1 Sia, Charmaine Si Min Critical Coronavirus Disease 2019 in a Hemodialysis Patient: A Proposed Clinical Management Strategy 2020-07-30 .txt text/plain 2859 161 43 We report our experience in treating the first case of COVID-19 in a HD patient in Singapore who had a severe clinical course including acute respiratory distress syndrome and propose a clinical management strategy. We also highlight the importance of early recognition and intervention for disease control, dialysis support in an acute hospital isolation facility, deisolation protocol, and discharge planning due to prolonged viral shedding. A case series of an outbreak in a dialysis center in Wuhan, where HD patients were observed to have a milder disease course or total absence of symptoms with lower levels of serum inflammatory cytokines, suggested that this is due to the inability to mount an effective cellular immune response and hence an absence of cytokine release syndrome [3] . We examined international guidelines provided by different centers [14] and proposed a workflow based on the time points of the clinical course of COVID-19 disease in ESKD patients (Fig. 3) . ./cache/cord-284979-lyt98od1.txt ./txt/cord-284979-lyt98od1.txt