id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-281130-9tawihti	Schirinzi, Annalisa	Pentraxin 3: Potential prognostic role in SARS-CoV-2 patients admitted to the emergency department	2020-11-02		.txt	text/plain	1037	58	49	(4) that evaluated the role of complement related pattern recognition molecules, including C-reactive protein (CRP) and Pentraxin 3 (PTX3), as markers of short-term mortality in intensive care patients. In order to evaluate the potential prognostic value of PTX3 and its correlation with the severity of SARS-CoV-2, measurement of PTX3 in serum samples of patients (n= 75, male/female 47/28, age 69 years (median) 59-75 years (IQR)) with COVID-19 microbiology proven infection (from March to May 2020) was carried out using an enzyme-linked immunosorbent assay (ELISA) (DSX, Technogenetics srl, Milano, Italy), in addition to routine laboratory tests performed at admission. Moreover, PTX3 correlated (Spearman test) with some inflammation biochemical parameters commonly evaluated in SARS-CoV-2 patients, in particular with IL-6 (r =0.69, p<0.001), PCT (r =0.52, p<0.001), PSP (r =0.52, p<0.001), LDH (r =0.62, p<0.001), CRP (r =0.59, p<0.001), and D-dimer (r =0.43, p<0.001). Taken together, data obtained from our preliminary study suggest a potential prognostic role of PTX3 in SARS-CoV-2 patients, with higher levels associated with poor outcome.	./cache/cord-281130-9tawihti.txt	./txt/cord-281130-9tawihti.txt