id author title date pages extension mime words sentences flesch summary cache txt cord-280551-9hoxy5ok Kim, Donghee Predictors of Outcomes of COVID-19 in Patients with Chronic Liver Disease: US Multi-center Study 2020-09-17 .txt text/plain 3585 189 49 We performed survival analysis to identify independent predictors of all-cause mortality and COVID-19 related mortality, and multivariate logistic regression to determine the risk of severe COVID-19 in patients with CLD. The liver-specific factors associated with independent risk of higher overall mortality were alcohol-related liver disease (ALD) (hazard ratio [HR] 2.42, 95% confidence interval [CI] 1.29-4.55), decompensated cirrhosis (HR 2.91 [1.70-5.00]) and hepatocellular carcinoma (HCC) (HR 3.31 [1.53-7.16]). Future studies will be needed to analyze specific subgroups within the spectrum of alcohol liver disease (ALD) who are at higher risk for adverse outcomes with COVID-19. We identify decompensated cirrhosis, ALD, and HCC to be determinants of mortality in patients with CLD, and additionally show that Hispanic ethnicity is independently associated with severe COVID-19. In this large study of 867 patients from 21 centers across the US with CLD with COVID-19 we determine that patients with alcohol related liver disease (ALD), decompensated cirrhosis and hepatocellular carcinoma have a high risk for allcause mortality from COVID-19. ./cache/cord-280551-9hoxy5ok.txt ./txt/cord-280551-9hoxy5ok.txt