id author title date pages extension mime words sentences flesch summary cache txt cord-270391-703js942 Rai, Harpreet K Atypical Presentation of Panhypopituitarism 2020-07-09 .txt text/plain 1699 116 41 Additional workup showed a deficiency of all the anterior pituitary hormones likely secondary to mass effect. Pituitary apoplexy, for example, presents with the rapid development of symptoms causing sudden impairment of adrenocorticotropic hormone (ACTH) secretion and, consequently, the sudden onset of cortisol deficiency symptoms. We describe a patient who presented following a syncopal episode with a wide range of differential diagnoses based on initial laboratory results, clinical course, and workup, ultimately leading to the diagnosis of panhypopituitarism. 2020 The patient was discharged with recommendations for outpatient follow-up with the endocrinology team for continued monitoring of his pituitary hormone level deficiencies and sellar mass. Patients admitted to the hospital for further workup of syncope usually undergo an extensive cardiac and neurological assessment. The patient presented above was diagnosed with a sellar mass leading to hyposecretion of all the pituitary hormones. Postural hypotension and syncope are the most common presentations of secondary adrenal insufficiency and panhypopituitarism. ./cache/cord-270391-703js942.txt ./txt/cord-270391-703js942.txt