id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-267788-ukz2wz4a	Jaffe, Allan S	Myocardial injury in severe COVID-19 infection	2020-06-07		.txt	text/plain	1909	121	51	[1] [2] [3] [4] In this issue of the European Heart Journal, the group from Wuhan Renmin University describe, in one of the larger cohorts (n = 671) reported to date, the importance of increases in cardiac troponin I (cTnI) in patients with a COVID-19 infection who were sick enough to require respiratory support. However, in critically ill patients, supply-demand imbalance leading to myocardial injury is more common, 10 due to the metabolic stress of the infection because of tachycardia, hypoxia, acidosis, and hypotension with or without substantial pre-existing epicardial coronary disease. Although arrhythmias have been described in the present and other studies of COVID-19, it is not clear that, in the absence of drugs that prolong the QTc interval which some now use as therapy, the incidence of these are greater than one might expect from patients with any severe respiratory infection leading to myocardial injury.	./cache/cord-267788-ukz2wz4a.txt	./txt/cord-267788-ukz2wz4a.txt