id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-024073-243addff	Richards, Guy	COVID-19 and the Rationale for Pharmacotherapy: A South African Perspective	2020-04-17		.txt	text/plain	3402	188	49	All of the patients had deteriorated despite routine therapies in the previous week, and the agent is now listed as a treatment option for severe or critical cases with elevated IL-6 in the National Health Commission of the People's Republic of China COVID-19 Diagnosis and Treatment Guide.(35) A very recent case study has described the successful use of Tmab in a patient on maintenance therapy for multiple myeloma who had received bortezomib, thalidomide and dexamethasone therapy approximately 4 years previously and had been on thalidomide maintenance since then. A systematic review of observational studies of corticosteroids administered to patients with SARS-CoV-1 reported no survival benefit and possible harm and increased mortality and secondary infections were noted with severe influenza A; however, the evidence quality was low.(43) A subsequent study noted in the WHO guidelines found no effect on mortality. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study	./cache/cord-024073-243addff.txt	./txt/cord-024073-243addff.txt